Perio Defend™ Periodontal Tray Therapy

Clinician delivered custom fabricated tray therapy designed to manage periodontal disease between dental visits.



Try Perio Defend Tray Therapy

$149 per case  |   Regular price $179

Help patients fight gum disease with 1.7% peroxide therapy in custom lab-made trays. Precision recesses and a peripheral gumline seal conform to each patient’s contours to keep gel in contact with teeth and gum tissue, minimizing displacement and supporting comprehensive full-arch care between visits.

Pocket Depth Reductions Nearly 3× Greater Than SRP Alone

Clinical studies evaluating tray delivery of 1.7% hydrogen peroxide gel alongside scaling and root planing demonstrated significantly greater improvements in pocket probing depth compared with SRP alone.

Up to 3×

Greater deep site probing depth reduction vs SRP alone at 26 weeks when tray plus 1.7% hydrogen peroxide treatment gel is used as an adjunct.

Source: Putt et al., Am J Dent 2014

(deep sites >5 mm: >1.10 mm vs 0.38 mm at 26 weeks).

Up to 59%

Of deep bleeding sites (>5 mm at baseline) improved to ≤5 mm by 26 weeks when tray plus 1.7% hydrogen peroxide treatment gel is used as an adjunct to SRP.he text area.

Source: Putt et al., Am J Dent 2014 (Fig. 5; 26 weeks).

Over 99.94%

tooth retention during periodontal maintenance observed over 2.5 to 5 years in a refractory case series using tray delivery with 1.7% hydrogen peroxide gel alongside ongoing professional care.

Source: Cochrane & Sindelar, J Clin Dent 2015 (case series).the text area

Give your patients a better way to fight gum disease

Brushing and flossing are essential but may not fully manage biofilm that accumulates around the gumline and between teeth. These bacterial communities can contribute to inflammation and periodontal tissue breakdown over time.

Perio Defend Tray Therapy uses a custom fabricated tray to help keep hydrogen peroxide treatment gel in place along the gumline during a short daily routine, supporting periodontal maintenance between professional visits.

The Science Behind Perio Defend

Biofilm is a primary driver of periodontal disease and can accumulate around the gumline and between teeth where routine brushing and flossing may be less effective.

Perio Defend uses a custom fabricated tray designed to help keep hydrogen peroxide treatment gel in place along the gumline during a short daily routine prescribed by the clinician.

As hydrogen peroxide breaks down it releases oxygen, helping create an environment less favorable for harmful bacteria while supporting periodontal maintenance between visits.

Clinical Evidence Supporting Tray Therapy

Published clinical research reports significant improvements in bleeding and probing outcomes when tray/gel therapy is used alongside scaling and root planing (SRP).

Evidence highlights

• Deep sites (>5 mm) showed mean probing depth reduction >1.10 mm with tray/gel adjunct therapy vs 0.38 mm with SRP alone at 26 weeks (P<0.001).
• Deep bleeding sites converting to ≤5 mm at 26 weeks: 59% / 53% (tray groups) vs 26% (SRP alone).

Tray design features

• Gumline seal / peripheral flange designed to help keep treatment gel where it’s placed during the session.
  
  
• Precision tooth recesses based on patient anatomy to improve stability and reduce gel displacement vs generic trays.
  
  
• Full-arch coverage to support consistent, repeatable use as part of a clinician-directed home-care plan.
  
  

Hydrogen peroxide’s gentle effervescence can help the gel spread around the gumline and between teeth during wear

Hydrogen Peroxide Tray Therapy
A Pocket Probing Depth Case Study

Getting to the Root of Periodontal Disease

Periodontal disease develops as bacteria organize into protective biofilm communities around the gumline and between teeth. These biofilms are protected by a sticky matrix that makes them difficult to disrupt with brushing and flossing alone. As biofilm accumulates, inflammation can increase and the supporting tissues around the teeth may become irritated despite good daily hygiene.

Perio Defend Tray Therapy is designed to support periodontal maintenance by pairing a custom fabricated tray with a hydrogen peroxide treatment gel. The tray helps keep the gel in place along the gumline during a short daily routine prescribed by the clinician. During wear, the gel’s gentle effervescence can help distribute the treatment around the gumline and between teeth.

Used as an adjunct to professional periodontal care, Perio Defend helps support disruption of biofilm and promotes a healthier oral environment between maintenance visits.

Bacteria can form structured communities called biofilm that accumulate around the gumline and between teeth, protected by a sticky matrix that helps them persist.

Brushing and flossing are essential for daily oral hygiene, but they may not fully address biofilm regrowth along the gumline and between teeth.



The Perio Defend approach helps patients manage bacterial regrowth using a comfortable custom tray system that helps keep treatment gel in place along the gumline during use.

Why partner with Bayshore Dental Studio

Bayshore Dental Studio fabricates Perio Defend trays customized for every patient with precision and consistency, ensuring accurate fit, predictable results, and reliable turnaround. Our team works closely with your practice to integrate Perio Defend seamlessly into your periodontal and maintenance workflows. Perio Defend is an Adjunct to professional periodontal care. Does not replace SRP or periodontal maintenance visits. Results vary.

Ideal Use Cases:

• Periodontal maintenance patients with bleeding/inflammation
• Moderate/advanced cases where between-visit consistency is a challenge
• Implant maintenance (peri-implant mucosal health support as directed)
• Patients who need a short, repeatable home routine adjunct to in-office therapy

Proven Benefits:

• Reduces bleeding and inflammation
• Supports biofilm disruption and oxygenation
• Enhances SRP and traditional in-office treatment
• Whiter teeth and fresher breath as a side benefit

Why It Works:

Hydrogen peroxide releases oxygen as it breaks down, helping create an environment less favorable for harmful bacteria while supporting a healthier microbial balance. Custom fabricated trays help keep treatment gel in place along the gumline during the treatment session.

Support Patient Health, Simplify Maintenance, Improve Results.

Extend periodontal care beyond the operatory with a simple, repeatable home routine.

Give your patients a practical way to support gum health between visits while providing your practice with a consistent tool for long term periodontal maintenance.

What Doctors Say About Perio Defend

— Dr. Lauren Mitchell, DMD

“Adding Perio Defend to our periodontal protocol has improved inflammation control and patient outcomes between hygiene appointments. It’s an effective extension of in office therapy.”

Frequently Asked Questions